Endocrine Abstracts

Diabetes melliuts (DM) presents particular challenges after kidney transplant (KT). These challenges contribute to cardiovascular disesases among diabetic recipients. We assessed frequency of posttransplant cardiovascular events in diabetic patients.Methods: This retrospective study conducted in 399 kidney recipients at our center. The patients were divided into two groups: DM (n:59, 52.5% females) and non-DM (n:340, 46.5% females).<p class="abstext"...

Renin angiotensin system blockers are currently used in the treatment of diabetic nephropathy. Carvedilol, 3. generation beta-blockers, may provide additional benefits in diabetic patients. Its antiproteinuric activity is not investigated in patients with diabetic nephropathy. We aimed to compare short-term additive effects of losartan with cilazapril or carvedilol combination on blood pressure, proteinuria and renal functions in microalbuminuric patients with type 2 diabetes ...

In hypertensive diabetic patients, renal angiotensin system blockers are first preferred due to their antihypertensive and antiproteinuric activities. Carvedilol, a third generation beta blocker, may provide additional benefits in diabetic patients. We aimed to compare the short-term efficacy of losartan treatment alone and in combination with cilazapril or carvedilol on blood pressure, glycemic control and lipid profile in microalbuminuric type 2 diabetic patients.<p clas...

In hypertensive diabetic patients, renal angiotensin system blockers are first preferred due to their antihypertensive and antiproteinuric activities. Carvedilol, a third generation beta blocker, may provide additional benefits in diabetic patients. We aimed to compare the short-term efficacy of losartan treatment alone and in combination with cilazapril or carvedilol on blood pressure, glycemic control and lipid profile in microalbuminuric type 2 diabetic patients.<p clas...

Calcineurin inhibitors (CNI, cyclosporine A: CsA and tacrolimus: Tac) cause posttransplant diabetes mellitus, hypercholesterolemia and hypertension. Post-transplant weight gain can be related to the type of CNIs. Distribution of obesity is one of the major predictors of cardiovascular diseases. Several indices assessed upper body obesity such as waist circumference (WC) and waist to hip ratio (WHR) are more accurate than whole body obesity (body mass index: BMI). This study ai...

Although serum calcium (Ca), phosphorus and parathyroid hormone (PTH) levels tend to normalize after successful kidney transplantation (KT), persistent hyperparathyroidism (PHPT) can have deleterious effects on graft function. We aimed to evaluate the effect of parathyroidectomy (PTx) on graft function in recipients after KT.Methods: This retrospective study conducted in 319 adult KT recipients. PHPT is defined as serum corrected Ca level >10.2 mg/dl...

After a successful kidney transplant, the nutrition of patients is improved and they gain weight. Increased appetite due to medication, age of transplant, gender, race, pre-transplant obesity story and dialysis type increase the obesity frequency. We aimed to evaluate the effect of gender on nutrition and exercise habits on transplant recipients.Methods: Stable patients were divided into two groups according to gender: 29 males and 33 females. Their nutr...

Vascular access remains both a life line and a ‘weak link for patients receiving hemodialysis (HD) therapy. It difficult to create an arteriovenous fistula (AVF) in diabetic hemodialysis patients due to atherosclerotic changes in arteries. This study investigated the fate of AVFs in diabetic and non-diabetic HD patients.Methods: The study included 306 patients (142 females, 164 males) on regular HD treatment with AVF. We excluded patients dialyzed w...

Obesity and cardiovascular disease (CVD) risk in recipients increase after kidney transplantation due to immunosuppressive drugs, non-traditional risk factors related to immunosuppressive drugs or chronic kidney disease (CKD). Inflammation, endothelial dysfunction, arterial stiffness (AS) and vascular calcification are common complications contributed to the development of CVD in patients with CKD. We aimed to evaluate the relationship between AS and obesity in transplant reci...

Acute pancreatitis in kidney transplant recipients is an infrequent complication with complex etiology. However, there was no enough data about chronic pancreatitis after kidney transplantation. Glucose intolerance occurs with some frequency in chronic pancreatitis, but overt diabetes mellitus usually occurs late in the course of the disease. We presented long-term course of a kidney transplant recipient who developed recurrent acute pancreatitis.Case re...